A16S (p.Ala16Ser) variant of UNG (Uracil-DNA glycosylase)
A16S (p.Ala16Ser) in UNG (Uracil-DNA glycosylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A16S (p.Ala16Ser) variant details
- p.Ala16Ser
- TOPMed rs1171393436
- gnomAD rs1171393436
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.06
- CADD 11.40
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available