T24S (p.Thr24Ser) variant of UNC80 (Protein unc-80 homolog)
T24S (p.Thr24Ser) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
T24S (p.Thr24Ser) variant details
- p.Thr24Ser
- gnomAD 2-209772143-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.572
- MetaLR 0.08
- MetaSVM -1.03
- CADD 22.90
- PolyPhen-2 0.62
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available