S73P (p.Ser73Pro) variant of UNC80 (Protein unc-80 homolog)
S73P (p.Ser73Pro) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
S73P (p.Ser73Pro) variant details
- p.Ser73Pro
- gnomAD 2-209775964-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- MetaLR 0.11
- MetaSVM -1.07
- CADD 24.00
- PolyPhen-2 0.28
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available