R35G (p.Arg35Gly) variant of UNC80 (Protein unc-80 homolog)
R35G (p.Arg35Gly) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
R35G (p.Arg35Gly) variant details
- p.Arg35Gly
- gnomAD 2-209773104-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- MetaLR 0.15
- MetaSVM -0.96
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available