Q41P (p.Gln41Pro) variant of UNC80 (Protein unc-80 homolog)
Q41P (p.Gln41Pro) in UNC80 (Protein unc-80 homolog) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
Q41P (p.Gln41Pro) variant details
- p.Gln41Pro
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.527
- MetaLR 0.17
- MetaSVM -0.85
- CADD 26.40
- PolyPhen-2 0.95
- SIFT 0.03
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available