P63S (p.Pro63Ser) variant of UNC80 (Protein unc-80 homolog)
P63S (p.Pro63Ser) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
P63S (p.Pro63Ser) variant details
- p.Pro63Ser
- 1000Genomes rs530266739
- ExAC rs530266739
- gnomAD rs530266739
- Missense
- Variant Prioritization Score for Impact Estimate 0.619
- MetaLR 0.24
- MetaSVM -0.66
- CADD 23.20
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.1e-06)
- Structural context available