P36L (p.Pro36Leu) variant of UNC80 (Protein unc-80 homolog)
P36L (p.Pro36Leu) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
P36L (p.Pro36Leu) variant details
- p.Pro36Leu
- gnomAD 2-209773108-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.636
- MetaLR 0.21
- MetaSVM -0.71
- CADD 26.60
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available