P21A (p.Pro21Ala) variant of UNC80 (Protein unc-80 homolog)
P21A (p.Pro21Ala) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
P21A (p.Pro21Ala) variant details
- p.Pro21Ala
- TOPMed rs2076607618
- gnomAD rs2076607618
- Missense
- Variant Prioritization Score for Impact Estimate 0.552
- MetaLR 0.07
- MetaSVM -1.06
- CADD 19.80
- SIFT 0.08
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)
- Structural context available