N56D (p.Asn56Asp) variant of UNC80 (Protein unc-80 homolog)
N56D (p.Asn56Asp) in UNC80 (Protein unc-80 homolog) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
N56D (p.Asn56Asp) variant details
- p.Asn56Asp
- NCI-TCGA Cosmic COSV5589
- cosmic curated COSV55892
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.523
- MetaLR 0.23
- MetaSVM -0.67
- CADD 24.50
- PolyPhen-2 0.72
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available