K37R (p.Lys37Arg) variant of UNC80 (Protein unc-80 homolog)
K37R (p.Lys37Arg) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
K37R (p.Lys37Arg) variant details
- p.Lys37Arg
- Ensembl rs2076675839
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- MetaLR 0.24
- MetaSVM -0.66
- CADD 24.70
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available