I72V (p.Ile72Val) variant of UNC80 (Protein unc-80 homolog)
I72V (p.Ile72Val) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
I72V (p.Ile72Val) variant details
- p.Ile72Val
- ExAC rs755392412
- gnomAD rs755392412
- Missense
- Variant Prioritization Score for Impact Estimate 0.477
- MetaLR 0.08
- MetaSVM -1.09
- CADD 19.90
- PolyPhen-2 0.90
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available