I69F (p.Ile69Phe) variant of UNC80 (Protein unc-80 homolog)
I69F (p.Ile69Phe) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
I69F (p.Ile69Phe) variant details
- p.Ile69Phe
- gnomAD 2-209775952-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.533
- MetaLR 0.23
- MetaSVM -0.64
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available