H59R (p.His59Arg) variant of UNC80 (Protein unc-80 homolog)
H59R (p.His59Arg) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
H59R (p.His59Arg) variant details
- p.His59Arg
- 1000Genomes rs201094113
- ExAC rs201094113
- gnomAD rs201094113
- Missense
- Variant Prioritization Score for Impact Estimate 0.497
- MetaLR 0.12
- MetaSVM -1.00
- CADD 22.40
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available