G60S (p.Gly60Ser) variant of UNC80 (Protein unc-80 homolog)
G60S (p.Gly60Ser) in UNC80 (Protein unc-80 homolog) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
G60S (p.Gly60Ser) variant details
- p.Gly60Ser
- gnomAD 2-209775925-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.653
- MetaLR 0.31
- MetaSVM -0.46
- CADD 27.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available