S150R (p.Ser150Arg) variant of UNC13D (Protein unc-13 homolog D)
S150R (p.Ser150Arg) in UNC13D (Protein unc-13 homolog D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S150R (p.Ser150Arg) variant details
- p.Ser150Arg
- TOPMed rs1442743528
- gnomAD rs1442743528
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.06
- CADD 15.70
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available