L15F (p.Leu15Phe) variant of UNC13D (Protein unc-13 homolog D)
L15F (p.Leu15Phe) in UNC13D (Protein unc-13 homolog D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L15F (p.Leu15Phe) variant details
- p.Leu15Phe
- gnomAD rs1468315530
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.12
- CADD 18.00
- PolyPhen-2 0.27
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available