H65Y (p.His65Tyr) variant of UNC13D (Protein unc-13 homolog D)
H65Y (p.His65Tyr) in UNC13D (Protein unc-13 homolog D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
H65Y (p.His65Tyr) variant details
- p.His65Tyr
- gnomAD rs1383311404
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.07
- CADD 17.80
- PolyPhen-2 0.02
- SIFT 0.29
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available