H45Y (p.His45Tyr) variant of UNC13D (Protein unc-13 homolog D)
H45Y (p.His45Tyr) in UNC13D (Protein unc-13 homolog D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
H45Y (p.His45Tyr) variant details
- p.His45Tyr
- TOPMed rs2064964449
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.08
- CADD 21.50
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available