G149S (p.Gly149Ser) variant of UNC13D (Protein unc-13 homolog D)
G149S (p.Gly149Ser) in UNC13D (Protein unc-13 homolog D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G149S (p.Gly149Ser) variant details
- p.Gly149Ser
- ExAC rs761868892
- TOPMed rs761868892
- gnomAD rs761868892
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.07
- CADD 13.50
- PolyPhen-2 0.04
- SIFT 0.64
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available