A115T (p.Ala115Thr) variant of UNC13D (Protein unc-13 homolog D)
A115T (p.Ala115Thr) in UNC13D (Protein unc-13 homolog D) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
A115T (p.Ala115Thr) variant details
- p.Ala115Thr
- TOPMed rs1267574358
- gnomAD rs1267574358
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.20
- CADD 26.50
- PolyPhen-2 0.70
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available