S5Y (p.Ser5Tyr) variant of UGT1A1 (UDP-glucuronosyltransferase 1A1)
S5Y (p.Ser5Tyr) in UGT1A1 (UDP-glucuronosyltransferase 1A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
S5Y (p.Ser5Tyr) variant details
- p.Ser5Tyr
- TOPMed rs1697391714
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.03
- CADD 0.06
- PolyPhen-2 0.09
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available