S42G (p.Ser42Gly) variant of UGT1A1 (UDP-glucuronosyltransferase 1A1)
S42G (p.Ser42Gly) in UGT1A1 (UDP-glucuronosyltransferase 1A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
S42G (p.Ser42Gly) variant details
- p.Ser42Gly
- Ensembl rs1575771994
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.27
- CADD 18.80
- PolyPhen-2 0.11
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available