S25T (p.Ser25Thr) variant of UGT1A1 (UDP-glucuronosyltransferase 1A1)
S25T (p.Ser25Thr) in UGT1A1 (UDP-glucuronosyltransferase 1A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S25T (p.Ser25Thr) variant details
- p.Ser25Thr
- ExAC rs751894919
- gnomAD rs751894919
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.11
- CADD 3.63
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available