S25F (p.Ser25Phe) variant of UGT1A1 (UDP-glucuronosyltransferase 1A1)
S25F (p.Ser25Phe) in UGT1A1 (UDP-glucuronosyltransferase 1A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S25F (p.Ser25Phe) variant details
- p.Ser25Phe
- gnomAD 2-233760361-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.23
- CADD 17.10
- PolyPhen-2 0.62
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available