L15V (p.Leu15Val) variant of UGT1A1 (UDP-glucuronosyltransferase 1A1)
L15V (p.Leu15Val) in UGT1A1 (UDP-glucuronosyltransferase 1A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L15V (p.Leu15Val) variant details
- p.Leu15Val
- Ensembl rs2125982719
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.17
- CADD 14.90
- PolyPhen-2 0.67
- SIFT 0.15
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available