L11P (p.Leu11Pro) variant of UGT1A1 (UDP-glucuronosyltransferase 1A1)
L11P (p.Leu11Pro) in UGT1A1 (UDP-glucuronosyltransferase 1A1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- 1000Genomes rs201984525
- ExAC rs201984525
- gnomAD rs201984525
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.15
- CADD 14.60
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available