R35L (p.Arg35Leu) variant of U2AF1 (Q01081)
R35L (p.Arg35Leu) in U2AF1 (Q01081) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
R35L (p.Arg35Leu) variant details
- p.Arg35Leu
- gnomAD 21-43104343-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.594
- REVEL 0.53
- MetaLR 0.37
- MetaSVM -0.08
- CADD 26.90
- PolyPhen-2 0.90
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available