L5M (p.Leu5Met) variant of U2AF1 (Q01081)
L5M (p.Leu5Met) in U2AF1 (Q01081) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
L5M (p.Leu5Met) variant details
- p.Leu5Met
- gnomAD 21-43107482-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.29
- MetaLR 0.40
- MetaSVM -0.46
- CADD 24.20
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available