K15T (p.Lys15Thr) variant of U2AF1 (Q01081)
K15T (p.Lys15Thr) in U2AF1 (Q01081) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
K15T (p.Lys15Thr) variant details
- p.Lys15Thr
- gnomAD 21-43107451-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.27
- MetaLR 0.19
- MetaSVM -0.75
- CADD 28.00
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.4e-06)
- Structural context available
- Literature evidence available