K15Q (p.Lys15Gln) variant of U2AF1 (Q01081)
K15Q (p.Lys15Gln) in U2AF1 (Q01081) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
K15Q (p.Lys15Gln) variant details
- p.Lys15Gln
- gnomAD 21-43107452-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.17
- MetaLR 0.23
- MetaSVM -0.66
- CADD 32.00
- PolyPhen-2 0.96
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 4.8e-06)
- Structural context available
- Literature evidence available