G10S (p.Gly10Ser) variant of U2AF1 (Q01081)
G10S (p.Gly10Ser) in U2AF1 (Q01081) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
G10S (p.Gly10Ser) variant details
- p.Gly10Ser
- gnomAD 21-43107467-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.29
- MetaLR 0.23
- MetaSVM -0.50
- CADD 24.10
- PolyPhen-2 0.12
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 2.2e-06)
- Structural context available
- Literature evidence available