V64A (p.Val64Ala) variant of TYK2 (P29597)
V64A (p.Val64Ala) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
V64A (p.Val64Ala) variant details
- p.Val64Ala
- TOPMed rs1399398857
- gnomAD rs1399398857
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.24
- CADD 16.70
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available