T52P (p.Thr52Pro) variant of TYK2 (P29597)
T52P (p.Thr52Pro) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
T52P (p.Thr52Pro) variant details
- p.Thr52Pro
- TOPMed rs1484227289
- gnomAD rs1484227289
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- REVEL 0.58
- CADD 24.80
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available