T172I (p.Thr172Ile) variant of TYK2 (P29597)
T172I (p.Thr172Ile) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
T172I (p.Thr172Ile) variant details
- p.Thr172Ile
- gnomAD rs1216286893
- Missense
- Variant Prioritization Score for Impact Estimate 0.0999
- REVEL 0.07
- CADD 11.30
- PolyPhen-2 0.09
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available