T137R (p.Thr137Arg) variant of TYK2 (P29597)
T137R (p.Thr137Arg) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T137R (p.Thr137Arg) variant details
- p.Thr137Arg
- ESP rs149044054
- ExAC rs149044054
- TOPMed rs149044054
- gnomAD rs149044054
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.05
- CADD 9.62
- PolyPhen-2 0.04
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available