S50P (p.Ser50Pro) variant of TYK2 (P29597)
S50P (p.Ser50Pro) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
S50P (p.Ser50Pro) variant details
- p.Ser50Pro
- TOPMed rs1387248228
- gnomAD rs1387248228
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.11
- CADD 13.30
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available