R106T (p.Arg106Thr) variant of TYK2 (P29597)
R106T (p.Arg106Thr) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
R106T (p.Arg106Thr) variant details
- p.Arg106Thr
- ExAC rs749206339
- gnomAD rs749206339
- Missense
- Variant Prioritization Score for Impact Estimate 0.827
- REVEL 0.81
- CADD 34.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available