Q139R (p.Gln139Arg) variant of TYK2 (P29597)
Q139R (p.Gln139Arg) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
Q139R (p.Gln139Arg) variant details
- p.Gln139Arg
- TOPMed rs2041749897
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.06
- CADD 11.50
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available