Q136H (p.Gln136His) variant of TYK2 (P29597)
Q136H (p.Gln136His) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
Q136H (p.Gln136His) variant details
- p.Gln136His
- ExAC rs762486838
- TOPMed rs762486838
- gnomAD rs762486838
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- REVEL 0.06
- CADD 8.07
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available