P37R (p.Pro37Arg) variant of TYK2 (P29597)
P37R (p.Pro37Arg) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
P37R (p.Pro37Arg) variant details
- p.Pro37Arg
- gnomAD rs978916286
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.24
- CADD 18.20
- PolyPhen-2 0.47
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available