P120S (p.Pro120Ser) variant of TYK2 (P29597)
P120S (p.Pro120Ser) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
P120S (p.Pro120Ser) variant details
- p.Pro120Ser
- 1000Genomes rs199807224
- ExAC rs199807224
- TOPMed rs199807224
- gnomAD rs199807224
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.08
- CADD 20.50
- PolyPhen-2 0.06
- SIFT 0.19
- Most common in the 1KG:CLM population (allele frequency 0.011)
- Structural context available