N116Y (p.Asn116Tyr) variant of TYK2 (P29597)
N116Y (p.Asn116Tyr) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
N116Y (p.Asn116Tyr) variant details
- p.Asn116Tyr
- TOPMed rs1361836365
- gnomAD rs1361836365
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.26
- CADD 25.50
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available