N116H (p.Asn116His) variant of TYK2 (P29597)
N116H (p.Asn116His) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
N116H (p.Asn116His) variant details
- p.Asn116His
- TOPMed rs1361836365
- gnomAD rs1361836365
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.19
- CADD 24.00
- PolyPhen-2 0.69
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available