M8I (p.Met8Ile) variant of TYK2 (P29597)
M8I (p.Met8Ile) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
M8I (p.Met8Ile) variant details
- p.Met8Ile
- TOPMed rs995711325
- gnomAD rs995711325
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.15
- CADD 0.09
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available