M25V (p.Met25Val) variant of TYK2 (P29597)
M25V (p.Met25Val) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
M25V (p.Met25Val) variant details
- p.Met25Val
- ExAC rs755570432
- gnomAD rs755570432
- Missense
- Variant Prioritization Score for Impact Estimate 0.0468
- REVEL 0.03
- CADD 0.35
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available