L73F (p.Leu73Phe) variant of TYK2 (P29597)
L73F (p.Leu73Phe) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
L73F (p.Leu73Phe) variant details
- p.Leu73Phe
- cosmic curated COSV53390
- TOPMed rs2041763923
- gnomAD rs2041763923
- Missense
- Variant Prioritization Score for Impact Estimate 0.663
- REVEL 0.67
- CADD 24.70
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available