L167P (p.Leu167Pro) variant of TYK2 (P29597)
L167P (p.Leu167Pro) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
L167P (p.Leu167Pro) variant details
- p.Leu167Pro
- gnomAD rs1421177533
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.71
- CADD 26.30
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available