K29Q (p.Lys29Gln) variant of TYK2 (P29597)
K29Q (p.Lys29Gln) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
K29Q (p.Lys29Gln) variant details
- p.Lys29Gln
- ExAC rs752684154
- TOPMed rs752684154
- gnomAD rs752684154
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.09
- CADD 15.20
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available