K157E (p.Lys157Glu) variant of TYK2 (P29597)
K157E (p.Lys157Glu) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
K157E (p.Lys157Glu) variant details
- p.Lys157Glu
- Ensembl rs956505107
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- REVEL 0.25
- CADD 24.30
- PolyPhen-2 0.77
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available