I90T (p.Ile90Thr) variant of TYK2 (P29597)
I90T (p.Ile90Thr) in TYK2 (P29597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
I90T (p.Ile90Thr) variant details
- p.Ile90Thr
- gnomAD rs1490056740
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.07
- CADD 15.30
- PolyPhen-2 0.01
- SIFT 0.48
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available